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Materials and methods Clinical samples of hepatocellular carcinoma patients Human hepatocellular carcinoma (HCC) cancer tumor tissues and matched adjacent tissues ( n = 20) were collected from Cancer Hospital Affiliated to Harbin Medical University for qRT- PCR, western blot and Eliza assays

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Elderly patients tend to have a greater frequency of decreased hepatic, renal, or cardiac function, and also have concomitant disease or receiving other drug therapy

The first-order dissociation reaction rate constant for RT-GSH is 20.3 10 3 s 1 , which is more than 500 times faster than that for ThiolQuant Green-GSH (35.7 10 6 s 1 )